use enough gun.

Worked with a guy who had a moose tag outside of Jackson Hole & he was disabled & legal to shoot from the road

Had not even checked into his hotel, saw a trophy moose, pulled over and harvested it with one shot from his old wooden stocked 338 win mag

You need penetration 1st and accurate shot placement 2ndly

9mm hard cast buffalo bore would work for black bear/elk and such if you can accurately hit the target

The 460/500 S&W hand cannon’s are all the rage, around here but chances are all you can accurately get off is 1 shot due to the violent recoil even if ported…

I’ve been looking around at 10mm just for the heck of it & keep coming back to the 44 magnum, not only is it a smidgen bigger, it drives a hard cast  305gr bullet at 1300fps and that’s going to rattle you fillings loose 🤣🤣🤣🤣🤣🤣🤣🤣🤣

I’ve been loading the 3” Colt python with BB 180gr hard cast when out/about in the mountains followed up with 1or 2 reloads of 158gr JHP anti human ammo 😂😂😂

I've never shot a 500, but did handle one out of curiosity at the store. My first thought was you'd need a wheelbarrow to cary it!